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目的分析内镜黏膜下剥离术(ESD)治疗老年(年龄≥65岁)单发早期胃癌患者的安全性和有效性。方法选取2012年2月至2015年7月单发早期胃癌患者100例,50例≥65岁患者作为观察组,50例<65岁患者作为对照组,均采用ESD治疗,对比两组治疗后1年复发率、并发症发生率、术后住院时间、术中出血量、手术时间等。结果观察组经过治疗后复发率4.00%、并发症发生率6.00%,对照组分别为6.00%和8.00%,差异无统计学意义(P>0.05);观察组术后住院时间(6.21±2.35)d、术中出血量(158.45±20.17)ml、手术时间(50.41±10.11)min,对照组分别为(7.15±2.11)d、(155.33±21.45)ml、(51.24±10.23)min,差异无统计学意义(P>0.05)。结论ESD治疗老年单发早期胃癌,可获得与中青年患者类似的较好的效果。
Objective To analyze the safety and efficacy of endoscopic submucosal dissection (ESD) in the treatment of elderly single-stage early-stage gastric cancer (age≥65 years). Methods From February 2012 to July 2015, 100 patients with early gastric cancer, 50 patients ≥65 years old as observation group and 50 patients <65 years old as control group were treated with ESD. Year recurrence rate, complication rate, postoperative hospital stay, intraoperative blood loss, operation time and so on. Results The recurrence rate and the incidence of complications were 4.00% and 6.00% in the observation group after treatment, respectively, with a difference of 6.00% and 8.00%, respectively, with no significant difference (P> 0.05). The postoperative hospital stay time (6.21 ± 2.35) d, intraoperative blood loss (158.45 ± 20.17) ml, operation time (50.41 ± 10.11) min and control group were (7.15 ± 2.11) d, (155.33 ± 21.45) ml and (51.24 ± 10.23) Significance (P> 0.05). Conclusion ESD treatment of elderly single early gastric cancer, and middle-aged patients with similar results can be obtained.