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目的调查吸毒人群不同吸毒方式,丙型肝炎病毒(HCV)和人类免疫缺陷病毒(HIV)感染及合并感染状况。方法对123名吸毒者和98名正常对照组血清用酶联免疫吸附试验进行抗HCV 和抗 HIV 检测。结果 HCV 感染率在静脉注射组(IDU)为28.9%非静脉注射组(nIDU)为3.0%,对照组为1.0%。IDU 与 nIDU 和正常对照组比较有非常显著性差异(均 p<0.01).而 nIDU 与对照组比较无显著性差异(p>0.05)。HIV 感染率在 IDU 为3.3%,nIDU 和对照组均无感染。IDU 的 HCV和 HIV 混合感染率为2.2%。结论在吸毒人群中静脉注射用药是 HCV 与 HIV 感染和混合感染的高危因素,IDU 中 HCV 和 HIV 混合感染率最高。
Objective To investigate the different modes of drug abuse, hepatitis C virus (HCV) and human immunodeficiency virus (HIV) infection and co-infection among drug users. Methods Serum samples of 123 drug addicts and 98 normal controls were tested for anti-HCV and anti-HIV by enzyme-linked immunosorbent assay. Results The prevalence of HCV infection was 28.9% in the IDU group and 3.0% in the non-intravenous group (nIDU) and 1.0% in the control group. There was a significant difference between IDU and nIDU group (all p <0.01), while there was no significant difference between nIDU group and control group (p> 0.05). HIV infection rate was 3.3% in IDU, nIDU and control group were not infected. IDU has a combined HCV and HIV prevalence of 2.2%. Conclusion Intravenous injection of HCV in drug addicts is a high risk factor for HCV and HIV infection and mixed infection, and the highest infection rate of HCV and HIV is found in IDU.