以辛烯基琥珀酸淀粉钠为壁材,对麻保沙星进行微囊化包埋。实验条件为n(麻保沙星)∶n(混合溶剂)=1∶9,辛烯基琥珀酸淀粉钠浓度20%,麻保沙星含量10%,真空度0.03 MPa,乳化剪切温度40℃,滴加时间60 min。所得微囊包封率99.5%。此过程操作简单,提供了麻保沙星新剂型的制备方法。 With sodium starch octenylsuccinate as wall material, Marbofloxacin was microencapsulated. The experimental conditions were: n (Marbofloxacin): n (mixed solvent) = 1: 9, sodium octenylsuccinate sodium concentration 20%, marbofloxacin 10%, vacuum 0.03 MPa, emulsification shear temperature 40 ℃, dropping time 60 min. The resulting microencapsulation rate of 99.5%. This procedure is simple to operate and provides a new method for the preparation of Marbofloxacin.