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目的探讨心肌肌钙蛋白(cTnI)对不稳定型心绞痛(UAP)患者的预后评价。方法选取我院住院的127例心绞痛患者,不稳定型心绞痛(UAP)68例和稳定性心绞痛(SAP)59例,41名健康成年人为对照组,观察UAP患者住院期间的心脏事件发生率。结果 (1)UAP组cTnI阳性率明显高于SAP组以及对照组(P<0.01)。(2)UAP组中随着Braunwald危险分级程度的增高,cTnI阳性率也随之增高(P<0.05)。(3)UAP组中cTnI阳性组不良心血管事件发生率明显高于cTnI正常组(P<0.05)。结论 cTnI是UAP患者严重心血管事件发生的危险性预测因子,可作为UAP危险分层的指标。
Objective To investigate the prognostic value of cardiac troponin (cTnI) in patients with unstable angina pectoris (UAP). Methods A total of 127 patients with angina pectoris, 68 patients with unstable angina pectoris (UAP) and 59 patients with stable angina pectoris (SAP) were enrolled in our hospital. 41 healthy adults were selected as the control group. The incidence of cardiac events during hospitalization in UAP patients was observed. Results (1) The positive rate of cTnI in UAP group was significantly higher than that in SAP group and control group (P <0.01). (2) The positive rate of cTnI in the UAP group increased with the Braunwald risk classification (P <0.05). (3) The incidence of adverse cardiovascular events in cTnI positive group was significantly higher in UAP group than in cTnI normal group (P <0.05). Conclusions cTnI is a risk predictor of serious cardiovascular events in patients with UAP and can be used as an indicator of risk stratification in patients with UAP.