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我院1980～1984年收治118例慢性顽固性心衰患者,一般利尿剂无效,对维持量的洋地黄极易中毒(62％),采用的综合治疗为:①及早识别洋地黄中毒,及时停药;②用极化液合并镁盐以改善细胞内低钾状态;③选用扩管药哌唑嗪、酚妥拉明、硝普钠、硫甲丙脯酸;④有高度水肿时应用皮质激素;⑤加用抗甲状腺药,以降低难治的快速心率。结果89例(75.4％)危重心衰患者病情好转,死亡19例(16.1％),对照组(1956～1960年)210例死亡78例(37.1％)。
Our hospital from 1980 to 1984 admitted to 118 cases of patients with chronic refractory heart failure, diuretics generally invalid, to maintain the amount of digitalis poisoning easily (62%), the use of comprehensive treatment: ① early identification of digitalis poisoning and promptly stopped Drug; ② combined with magnesium chloride solution to improve the intracellular hypokalemic state; ③ choice of piperazine prazosin, phentolamine, sodium nitroprusside, thiotecan; ④ a high degree of edema when the application of corticosteroids ; ⑤ plus anti-thyroid drugs, to reduce the refractory fast heart rate. Results 89 cases (75.4%) of the critically ill patients with heart failure improved in condition, 19 (16.1%) died and 210 (37.1%) died in the control group (1956 ~ 1960).