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目的 为了探讨解脲支原体 (Uu)不同血清型与致病性关系。方法 对来自STD门诊的1 72株Uu作了 1～ 1 4型血清学分型。Uu株经纯化后 ,应用代谢抑制试验判定。结果 可分型Uu株达到 1 0 0 % ,属单一型有 1 5 0株 ( 87 2 % ) ,混合型占 2 2株 ( 1 2 8% )。出现频率高的血清型依次为 :4型3 1株 ( 1 5 4% ) ,1型 3 1株 ( 1 5 4% ) ,3型 2 4株 ( 1 1 9% ) ,8型 2 0株 ( 1 0 % ) ,1 4型 1 8株 ( 9% ) ,6型 1 6株( 8% ) ,其他血清型较少 (占 3 %～ 6 5 % ) ,未见 7型Uu株。结果显示 ,血清型与性别无关 (P >0 0 5 ) ,但非淋菌性尿道炎患者 3型Uu株女性多于男性 (P <0 0 5 )。 1 72株中 1 0 2株Uu系由非淋菌性尿道炎患者的标本中分离出 ,单一型占 90株 ( 88 2 % ) ,混合型占 1 2株 ( 1 1 8% )。出现频率高的血清型为 4、1和8型 ,各占 1 0 %以上。其中以 4型为最高 ,占 2 5株 ( 2 1 6 % )。结论 4型与非淋菌性尿道炎发生呈显著相关。作者认为 ,Uu株 3型在宿主因素和一定的环境条件下 ,寄居和致病状态可相互转化
Objective To explore the relationship between different serotypes and pathogenicity of Uu mycoplasma (Uu). Methods One hundred and seventy-eight Uu strains from STD clinic were enrolled in this study. Uu strain after purification, the application of metabolic inhibition test. Results The type of Uu strain was 100%. There were 150 strains (87.2%) of single type and 22 strains (122%) of mixed type. Serotypes with high frequency of occurrence were 4 1 (15.4%), 3 1 (15.4%) of type 1, 24 strains of type 3 (1 1 9%) and 20 strains of type 8 (10%), 14 strains (14%) of 14 strains, 16 strains (6%) of 6 strains (8%), and the other serotypes were less (3% ~ 65%). The results showed that the serotype was not related to sex (P> 0.05), but there were more female than female in type 3 Uu in non-gonococcal urethritis (P <0.05). Of the 72 strains, 102 strains of Uu were isolated from specimens of patients with nongonococcal urethritis, accounting for 90 (88.2%) in the single type and 12 (118%) in the mixed type. High frequency of serotypes 4,1 and 8, each accounting for more than 10%. Among them, Type 4 was the highest, accounting for 25 (21.6%). Conclusion There is a significant correlation between type 4 and non-gonococcal urethritis. The authors believe that, Uu strain type 3 in the host factors and under certain environmental conditions, habitat and pathogenic conditions can be transformed into each other