探讨超声波预处理反应原料脱乙酰化制备壳聚糖的适宜条件。甲壳素和50%NaOH经超声波预处理1h后,在90℃下搅拌反应10h,获得壳聚糖的脱乙酰度为88.89%,黏度为98cp。本工艺仅对反应原料进行超声波预处理,不必改变传统制备工艺条件,产品脱乙酰度提高10%以上。 To explore the suitable conditions for the preparation of chitosan by deacetylation of the reaction raw materials by ultrasonic pretreatment. Chitin and 50% NaOH were ultrasonic pretreatment 1h, the reaction was stirred at 90 ℃ 10h, the degree of deacetylation of chitosan was 88.89%, the viscosity of 98cp. The present process only pretreats the raw materials for the reaction without changing the traditional preparation process conditions, and the degree of deacetylation of the product is increased by more than 10%.