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子宫肌瘤是女性生殖器官中最常见的良性肿瘤,为研究子宫肌瘤的发病原因,本研究对38例子宫肌瘤患者血清中的雌二醇(E_2)孕酮(P)睾酮(T)垂体催乳素(PRL)。 促卵泡激素(FSH)黄体生成素(LH)等6种性激素水平做了测定,并以正常妇女为对照,以探讨其变化与子宫肌瘤病因的关系。1 资料与方法1.1 实验组 38例选自1997年8月～1998年3月在我院住院的子宫肌瘤患者,其中宫内膜增生期17例,分泌期21例。肌间肌瘤33例,浆膜下肌瘤3例,粘膜下肌瘤2例。所有病例经手术及病理检查确诊为子宫平滑肌瘤,近3个月内未使用激素类的避孕药及影响PRL水平的药物,无影响PRL分泌的疾病,近年内无分娩及长期哺乳史。
Uterine fibroids are the most common benign tumors in female genital organs. In order to study the pathogenesis of uterine fibroids, we studied the correlation between serum estradiol (E2) and progesterone (T) in 38 cases of uterine fibroids. Pituitary prolactin (PRL). Follicle stimulating hormone (FSH) luteinizing hormone (LH) and other six sex hormones levels were measured and normal women as a control to explore the relationship between changes and the etiology of uterine fibroids. 1 Materials and Methods 1.1 experimental group of 38 patients selected from August 1997 to March 1998 in our hospital in patients with uterine fibroids, including 17 cases of endometrial hyperplasia, secretory phase in 21 cases. 33 cases of intramuscular myoma, 3 cases of subserosal fibroids, 2 cases of submucous myoma. All cases were diagnosed as uterine leiomyoma by operation and pathological examination. No hormonal contraceptives and PRL-related drugs were used in the past 3 months, no diseases affecting the secretion of PRL, and no history of childbirth and long-term lactation in recent years.