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目的:分析新生儿出生缺陷发生率及其特征,研究和探讨干预措施。方法:对2000~2006年住院分娩的围产儿进行监测,对筛查出的1006例出生缺陷儿相关因素进行分析。结果:出生缺陷发生率平均为17.40‰,农村发生率高于城市,出生缺陷特征以胎儿水肿综合征居首位,孕母年龄≥35岁组出生缺陷的发生率高于年龄<35岁组。结论:加强婚前、孕期健康教育和围产期保健工作,提高产前筛查和产前诊断技术,采取综合干预措施可有效降低出生缺陷发生率。
Objective: To analyze the incidence of neonatal birth defects and their characteristics, to study and explore interventions. Methods: The perinatal hospitalization was monitored from 2000 to 2006, and the related factors of 1006 cases of birth defects were analyzed. Results: The average incidence of birth defects was 17.40 ‰. The incidence in rural areas was higher than that in urban areas. The birth defects were the most common in fetal edema syndrome. The incidence of birth defects in pregnant women ≥35 years old was higher than that of 35 years old. Conclusion: To strengthen prenuptial and prenatal health education and perinatal health care, to improve prenatal screening and prenatal diagnosis techniques, comprehensive interventions can effectively reduce the incidence of birth defects.