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目的探讨子宫内膜癌术前临床分期的应用价值。方法汕头大学肿瘤医院1996年1月至2004年6月对68例子宫内膜癌患者行术前超声检测、诊断性刮宫以及血清CA125水平测定后进行临床分期,并与术后手术病理分期进行比较。结果(1)超声诊断子宫内膜癌肌层浸润程度的准确率为868%;(2)诊断性刮宫诊断宫颈管是否受侵的准确率为912%;(3)子宫内膜癌I期血清CA125水平明显低于Ⅱ、Ⅲ、Ⅳ期,且手术病理分期愈晚,血清CA125的水平也愈高;(4)三种方法术前综合判断子宫内膜癌临床分期的准确率为824%。结论超声、诊断性刮宫以及血清CA125水平联合检测可提高子宫内膜癌术前临床分期的准确率,具较好的临床应用价值。
Objective To investigate the clinical value of preoperative clinical staging of endometrial cancer. Methods Tumor Hospital of Shantou University from January 1996 to June 2004 in 68 cases of endometrial cancer patients underwent preoperative ultrasound examination, diagnostic curettage and serum CA125 levels after clinical staging, and postoperative pathological staging were compared . Results (1) The accuracy of ultrasonic diagnosis of myometrial invasion was 868%. (2) The diagnostic accuracy of diagnostic curettage of cervical canal was 912%. (3) The endometrial carcinoma stage I serum The level of CA125 was significantly lower than that of stage II, III and IV. The later the pathological stage was, the higher the level of serum CA125 was. (4) The accuracy of the three methods for preoperative determination of clinical staging of endometrial cancer was 824%. Conclusion The combination of ultrasound, diagnostic curettage and serum CA125 levels can improve the accuracy of preoperative clinical staging of endometrial cancer with better clinical value.