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本文介绍了CA19-9免疫放射分析方法的临床应用,其中测定96名正常人血清的平均值为8.32±7.23U/mL,73名结-直肠患者血清(包括DukeA、B、C、D期)的平均值分别为9.68±5.32U/mL、12.87±10.14U/mL、71.11±90.53U/mL、297.55±255.11U/mL。60例胰腺癌血清平均值为196.12±208.30U/mL。若以30U/mL为阳性界值,其结一直肠癌DukeA、B、C、和D期阳性率分别为0%、13.8%、46.7%和87.5%。胰腺癌阳性率为80%。正常人假阳性率为1.04%。本文还应用ROC分析法论证CA19-9IRMA在临床中的应用价值。
This article describes the clinical application of CA19-9 immunoradiometric assays, in which the average of 96 normal human sera was determined to be 8.32±7.23 U/mL, and 73 patients with colorectal cancer (including Duke A, B, C, The average value of D phase) was 9.68±5.32 U/mL, 12.87±10.14 U/mL, 71.11±90.53 U/mL, and 297.55±255.11 U/mL, respectively. The average serum level of 60 cases of pancreatic cancer was 196.12±208.30 U/mL. With 30 U/mL as a positive cutoff, the positive rates of Duke A, B, C, and D in colon cancer were 0%, 13.8%, 46.7%, and 87.5%, respectively. The positive rate of pancreatic cancer was 80%. The normal false positive rate was 1.04%. This article also applied ROC analysis to demonstrate the clinical value of CA19-9IRMA.