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目的:探讨研究脑钠肽在慢性心力衰竭中的诊断价值及在其预后评估的中应用。方法:分析我院96例心衰患者资料,根据检查BNP值将患者分为BNP100-400pg/mL组、BNP400-100pg/mL组、BNP>1000pg/mL三组,比较三组的LVEF值及一年死亡率。结果:BNP100-400pg/mL组LVEF的平均值为43±13,一年内死亡率4.55%,BNP400-100pg/mL组LVEF的平均值为33±6,一年内死亡率22.06%;BNP>1000pg/mL组LVEF的平均值为25±3,一年内死亡率33.33%。经计算得出χ2=7.9717,P=0.0186,有统计学意义。结论:慢性心力衰竭患者的脑钠肽值与LVEF值呈正相关,且随着脑钠肽值的升高患者的死亡率也升高。
Objective: To investigate the diagnostic value of brain natriuretic peptide in chronic heart failure and its application in prognosis evaluation. Methods: The data of 96 patients with heart failure in our hospital were analyzed. Patients were divided into BNP100-400pg / mL group, BNP400-100pg / mL group and BNP> 1000pg / mL group according to BNP value. The LVEF values of three groups were compared Annual mortality. Results: The average LVEF of BNP100-400pg / mL group was 43 ± 13, the one-year mortality rate was 4.55%, the average LVEF of BNP400-100pg / mL group was 33 ± 6, the one-year mortality rate was 22.06%; BNP> 1000pg / mL group LVEF average of 25 ± 3, one-year mortality rate of 33.33%. Calculated χ2 = 7.9717, P = 0.0186, with statistical significance. CONCLUSIONS: There is a positive correlation between BNP and LVEF in patients with chronic heart failure, and their mortality is also increased with the increase of brain natriuretic peptide.