P-26 Effects of Panax notoginseng saponins on cerebral edema postburn stress and its relationship wi

来源 :Acta Pharmacologica Sinica | 被引量 : 0次 | 上传用户:hmei_0
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Cerebral edema postbum stress is one of the main lethal causes of burn patients, however, almost little was known about its mechanisms and effective prophylactic agents.In our previous study, it was found that there was a significant correlation between the increment of nitric oxide (NO) and pulmonary edema post-smoke inhalation injury stress.Herein, in this study, we further investigated any possible role of NO in cerebral edema postburn stress and its treatment.The results showed that water content of hypothalamus began to elevate at 30 min, reached peak at 1 h, Cerebral edema postbum stress is one of the main lethal causes of burn patients, however, almost little was known about its mechanisms and effective prophylactic agents.In our previous study, it was found that there was a significant correlation between the increment of nitric oxide ( NO) and pulmonary edema post-smoke inhalation injury stress.Herein, in this study, we further investigated any possible role of NO in cerebral edema postburn stress and its treatment.The results showed that water content of hypothalamus began to elevate at 30 min, Reached peak at 1 h,
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