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目的：测定甲状腺正常组织及良性结节的雌、孕激素受体表达，以了解甲状腺疾病与雌、孕激素的关系。方法：以葡聚糖活性碳饱和分析法测试人正常甲状腺组织２０例良性结节各１０例及其雌、孕激素受体的表达。结果：（１）人正常甲状腺组织中雌、孕激素受体分别有６例（６／２０）、７例（７／２０）阳性表达；（２）甲状腺腺瘤的雌、孕激素受体的表达分别有５例（５／１０）、６例（６／１０）；（３）结节性甲状腺肿的雌、孕激素受体表达分别有５例（５／１０）、６例（６／１０）。结论：甲状腺良性结节的发生发展过程与雌、孕激素有关，对女性或孕期妇女易罹患甲状腺疾病这一现象可做出一定的解释。
Objective: To determine the expression of estrogen and progesterone receptors in normal thyroid tissue and benign nodules in order to understand the relationship between thyroid disease and estrogen and progesterone. Methods: The expression of estrogen receptor and progesterone receptor in 10 cases of benign nodules and 10 cases of normal thyroid tissue in normal thyroid tissue were detected by dextran activated carbon saturation analysis. Results: (1) The expression of estrogen and progesterone receptor in normal thyroid tissue was 6 (6/20) and 7 (7/20) respectively. (2) The expression of estrogen and progesterone receptor in thyroid adenoma (5/10) and 6 cases (6/10) respectively. (3) The expressions of estrogen and progesterone receptor in nodular goiter were 5 (5/10) and 6 (6 / 10). Conclusion: The occurrence and development of benign thyroid nodules are related to estrogen and progesterone, and may explain the phenomenon of thyroid disease easily experienced by women or pregnant women.