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本文应用立体学原理对存在于舌粘膜、十二指肠及腺样肝肿瘤等不同组织中的肥大细胞的形态特征进行了定量分析。通过测算得出,位于舌组织中的结缔组织肥大细胞与十二指肠粘膜中的粘膜肥大细胞内的颗粒数密度(其±SE分别为3.439±0.020和1.646±0.023个数/μm~3)、颗粒平均直径(分别为0.450±0.003和0.550±0.005μm)和细胞核的P/D之比(3.180±0.012和3.930±0.030)均有显著性差异(P<0.01)。腺样肝肿瘤中的肥大细胞各成分的测量数据与结缔组织肥大细胞明显不同,而与粘膜肥大细胞相近似。这一结果与我们对该细胞所作的组织化学反应结果一致,提示形态测量技术可作为鉴别不同类型肥大细胞的一种可靠方法。
In this paper, the morphological characteristics of mast cells present in different tissues such as tongue mucosa, duodenum and adenoid liver tumors were quantitatively analyzed using the principle of stereology. The number density of the number of connective tissue mast cells in the tongue and mucosal mast cells in the duodenal mucosa was calculated (±SE = 3.439±0.020 and 1.646±0.023 counts/μm~3, respectively). The average particle diameter (0.450±0.003 and 0.550±0.005 μm, respectively) and the P/D ratio of the nucleus (3.180±0.012 and 3.930±0.030) were significantly different (P<0.01). The measurement data of the components of mast cells in adenoid liver tumors are significantly different from that of connective tissue mast cells, which are similar to mucosal mast cells. This result is consistent with the results of our histochemical reactions on the cells, suggesting that morphometric techniques can be used as a reliable method for identifying different types of mast cells.