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目的观察大黄与丹参对重症急性胰腺炎(SAP)患者血清胃泌素、胆囊收缩素水平的影响。方法将入选的SAP患者分为试验组(27例)和对照组(25例),试验组在常规治疗方法基础上予以大黄与丹参治疗,对照组予以常规方法治疗。治疗前和治疗后1周行血清胃泌素、胆囊收缩素水平检测。血清胃泌素和胆囊收缩素水平采用ELASA方法检测。结果与对照组比较,试验组胃泌素水平下降(P<0.01);胆囊收缩素水平升高(P<0.05)。结论大黄和丹参治疗SAP患者,可以使其胃泌素水平下降和胆囊收缩素水平升高。
Objective To observe the effect of rhubarb and salvia miltiorrhiza on serum gastrin and cholecystokinin in patients with severe acute pancreatitis (SAP). Methods The selected SAP patients were divided into experimental group (n = 27) and control group (n = 25). The experimental group was treated with rhubarb and salvia miltiorrhiza on the basis of routine treatment and the control group was treated by routine method. Serum gastrin and cholecystokinin levels were measured before treatment and 1 week after treatment. Serum gastrin and cholecystokinin levels were measured using the ELASA method. Results Compared with the control group, the level of gastrin decreased (P <0.01) and the level of cholecystokinin increased (P <0.05). Conclusion Rhubarb and salvia miltiorrhiza treatment of SAP patients, can make its gastrin levels and cholecystokinin levels.