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目的了解宁波市2005年出生儿童流行性腮腺炎(简称流腮)的流行病学特征及流腮成分疫苗保护效果。方法采用回顾性队列研究方法,按照流腮成分疫苗接种情况对宁波市2005年出生儿童进行分组,比较各组流腮报告发病情况。结果 2005-2014年观察儿童中流腮病例共400例,年平均发病率为97.76/10万。免疫组平均年发病率为76.47/10万,未免疫组平均年发病率为448.53/10万。接种1剂次组RR=0.18,接种2~3剂次组RR=0.07。结论宁波市2005年出生儿童流腮季节性和周期性分布明显,发病高峰在6~7岁。免疫组与未免疫组发病率差异有统计学意义,接种2~3剂次较接种1剂次保护率更高。
Objective To understand the epidemiological characteristics of mumps (mumps) born in Ningbo City in 2005 and the protective effect of mumps vaccine. Methods A retrospective cohort study was conducted to classify the children born in Ningbo in 2005 according to the gonococcal vaccine. The incidence of rump cheeks in each group was compared. Results A total of 400 mumps cases were observed in children from 2005 to 2014, with an average annual incidence of 97.76 / 100 000. The average annual incidence of immunization group was 76.47 / 100,000, the average annual incidence of non-immunized group was 448.53 / 100,000. Inoculation 1 dose group RR = 0.18, inoculation 2 to 3 dose group RR = 0.07. Conclusion The seasonal and periodic distribution of gills in born children in Ningbo in 2005 is obvious. The peak incidence is between 6 and 7 years old. The difference between the immunized group and the non-immunized group was statistically significant. The protective rate of 2 to 3 doses was higher than that of 1 dose.