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经硬膜外腔注入布比卡因常作为剖宫产术后镇痛的一种方法。为加强镇痛效果和延长镇痛时间,我们在布比卡因基础上复合咪唑安定,取得较好的效果,报告如下。 1 资料与方法 1.1 病例选择:选择需剖宫产患者45例,ASAⅠ级,年龄25～30岁,体重65～85kg,手术时间<1h。随机分为三组:咪唑安定(Ⅰ)组,咪唑安定/布比卡因(Ⅱ)组,布比卡因(Ⅲ)组,每组15例。 1.2 治疗方法:不予术前药,T_(12-1)间隙穿刺至硬膜外导管,经硬膜外导管注2％利多卡因5ml试验无误,5分钟后推注0.375％布比卡因、1％利多卡因混合液10ml,术毕前分别硬膜外注等容咪唑安定(0.08mg/kg,Ⅰ组),咪唑安定0.08mg/kg及0.25％布比卡因(Ⅱ组),0.25布比卡因(Ⅲ组)。 1.3 监测方法:回房连续每15分钟记录血压、
Bupivacaine is often injected via the epidural space as a method of analgesia after cesarean section. In order to strengthen the analgesic effect and prolong the analgesic time, we combined with midazolam on the basis of bupivacaine and achieved good results. The report is as follows. 1 Materials and Methods 1.1 Case Selection: 45 cases of cesarean section were selected, ASA Ⅰ grade, aged 25 to 30 years old, body weight 65 ~ 85kg, operation time <1h. They were randomly divided into three groups: midazolam (Ⅰ) group, midazolam / bupivacaine (Ⅱ) group and bupivacaine (Ⅲ) group, 15 cases in each group. 1.2 Treatment: no preoperative drugs, T_ (12-1) gap punctures to the epidural catheter, epidural catheter injection of 2% lidocaine 2ml test correct, 5 minutes after injection of 0.375% bupivacaine , 1% lidocaine mixture 10ml, respectively, before the completion of the epidural infusion of midazolam (0.08mg / kg, Ⅰ group), midazolam 0.08mg / kg and 0.25% bupivacaine (Ⅱ group), 0.25 Bupivacaine (group Ⅲ). 1.3 monitoring methods: back to the room for 15 minutes continuous recording of blood pressure,