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目的为了比较甲硝唑不同剂型给药对滴虫阴道炎临床疗效。方法总结在我院治疗的滴虫阴道炎患者84例资料,按照患者自主选择的药物剂型进行分组:选用甲硝唑棒局部给药的30例为治疗一组,选用甲硝唑片剂口服给药的26例为治疗二组,选用甲硝唑液进行局部清洗给药的28例为治疗三组,治疗后按照文中疗效标准进行评定,最后统计学方法比较组间差异性。结果治疗一组显效23例(76.7%),有效29例(96.7%),治疗二组显效14例(53.8%),有效20例(76.9%),治疗三组显效8例(28.6%),有效20例(71.4%),治疗一组疗效结果明显优于另外两组(P<0.05)。结论甲硝唑棒状剂型通过局部给药方式治疗妇产科滴虫阴道炎具有满意的临床疗效。
Objective To compare the clinical efficacy of different dosage forms of metronidazole on trichomoniasis vaginitis. Methods The data of 84 patients with trichomonas vaginitis treated in our hospital were divided into groups according to the drug dosage forms selected by the patients. Thirty patients with local administration of metronidazole rods were treated with one group. Metronidazole tablets were administered orally Twenty-six cases were treated with metronidazole and 28 cases were treated with metronidazole solution. Three groups were treated by metronidazole solution. After treatment, the efficacy was evaluated according to the standard of curative effect. The statistical method was used to compare the differences between groups. Results In the treatment group, 23 cases (76.7%) were markedly effective, 29 cases (96.7%) were effective, 14 (53.8%) were effective in the two groups, 20 (76.9% Effective in 20 cases (71.4%), the results of a treatment group was significantly better than the other two groups (P <0.05). Conclusion The metronidazole rod-shaped preparation has satisfactory clinical efficacy in the treatment of vaginitis in obstetrics and gynecology by topical administration.