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目的观察甲氨蝶呤联合米非司酮治疗异位妊娠的临床疗效。方法选取我院收治的100例异位妊娠患者,随机分成观察组和对照组,两组患者均给予甲氨蝶呤单次肌肉注射,观察组患者在此基础上于甲氨蝶呤单次注射第二天给予米非司酮口服。结果两组患者包块大小、血β-人绒毛膜促性腺激素、血孕酮值及治疗总有效率差异有统计学意义,P<0.05。两组患者不良反应比较无显著差异,P>0.05。结论甲氨蝶呤联合米非司酮治疗异位妊娠疗效可靠,无明显不良反应,是药物治疗异位妊娠的理想方案。
Objective To observe the clinical efficacy of methotrexate combined with mifepristone in the treatment of ectopic pregnancy. Methods 100 cases of ectopic pregnancy admitted to our hospital were randomly divided into observation group and control group, both groups were given a single intramuscular injection of methotrexate, on the basis of which patients in the observation group were given a single injection of methotrexate The next day to give mifepristone orally. Results The two groups of patients with mass size, serum β-human chorionic gonadotropin, blood progesterone value and total effective rate difference was statistically significant, P <0.05. Adverse reactions between the two groups showed no significant difference, P> 0.05. Conclusion Methotrexate combined with mifepristone treatment of ectopic pregnancy reliable, no significant adverse reactions, is the ideal solution for drug treatment of ectopic pregnancy.