论文部分内容阅读
目的探讨PHP动作对载人离心机致加速度性肺不张的防护作用。方法试验采用的模拟空战曲线(SACM)包括2个各45 s的+4.5 Gz和2个分别为15 s和45 s的+5.0 Gz的平台,基线为+3.0 Gz(各30 s)。7名志愿者呼吸浓度为100%的O2,在3种条件下进行SACM离心机暴露:A组,O2系统安全余压打开;B组,O2系统安全余压关闭;C组,O2系统安全余压关闭且采用PHP动作。结果 SACM暴露后,A组肺活量(VC)下降0.27 L,用力肺活量(FVC)和用力呼气量(FEV)均无显著变化,主观症状评分较低(2.5±2.6),胸部X线成像改变不明显。B组VC和FVC分别下降0.69 L(P<0.01)和0.29 L(P<0.05),咳嗽、胸痛、吸气困难等主观症状明显,其评分(8.1±2.2)显著高于有安全余压时(P<0.05),出现肺不张的典型影像学表现。C组VC和FVC无明显下降,无明显主观症状,主观感觉评分很低(0.8±0.9),与不采用PHP动作时的差异非常显著(P<0.01),肺不张的影像学征象比不采用PHP动作时明显减轻。结论采用PHP动作能够有效防止加速度性肺不张的发生。
Objective To explore the protective effect of PHP motion on induced atelectasis in manned centrifuges. The SACM used in the method test consisted of two +4.5 Gz of 45 s each and two +5.0 Gz platforms of 15 s and 45 s, respectively, with a baseline of +3.0 Gz (each 30 s). Seven volunteers with 100% respiration O2 were exposed to SACM centrifuge under three conditions: Group A, O2 system safety residual pressure opened; Group B, O2 system safety residual pressure closed; Group C, O2 system safety Press close and use PHP action. Results After SACM exposure, the vital capacity (VC) in group A decreased by 0.27 L, and the FVC and FEV showed no significant changes. The score of subjective symptom was lower (2.5 ± 2.6) and chest X-ray did not change obvious. The VC and FVC in group B decreased by 0.69 L (P <0.01) and 0.29 L (P <0.05), respectively. The subjective symptoms such as cough, chest pain and inspiratory difficulty were significantly lower than those in group B (8.1 ± 2.2) (P <0.05), the typical imaging findings of atelectasis. The VC and FVC in group C showed no significant decrease, no obvious subjective symptoms, subjective sensory score was very low (0.8 ± 0.9), which was significantly different from those without PHP (P <0.01). The imaging signs of atelectasis were not significant Significantly reduced when using PHP action. Conclusion The use of PHP action can effectively prevent the occurrence of accelerated atelectasis.