胰岛素瘤占胰腺内分泌肿瘤的80%~85%[1,2],其临床表现多种多样,常伴有神经精神系统的症状,影像学检查常不易发现,很容易误诊误治。80年代以来随着B超仪器的改进和高频探头的出现,术中超声(IOUS)应用于临床。自1982年Lane等[3]首先报道IOUS用于探测胰岛素瘤以来,相继有不少成功? Insulin tumors account for 80% to 85% of pancreatic endocrine tumors [1,2]. The clinical manifestations are diverse and often accompanied by neuropsychiatric symptoms. Radiographic examination is often not easy to find and it is easy to misdiagnosis and mistreatment. Since the 1980s with the B ultrasound instrument improvements and the emergence of high-frequency probe, intraoperative ultrasound (IOUS) used in clinical. Since Lane et al [3] first reported that IOUS was used to detect insulinoma in 1982, there have been many success stories in succession.