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选择本院2011年7月~2014年7月收治的169例PD,随机分为治疗组88例和对照组81例。观察比较两组临床有效率及副作用。治疗后及治疗后3个月,观察组“开”期时间显著升高,而“关”期时间显著下降,差异有统计学意义(P<0.05)。恩他卡朋联合左旋多巴治疗可明显缓解PD症状,疗效优于单纯左旋多巴治疗,值得临床推广。
169 cases of PD treated in our hospital from July 2011 to July 2014 were randomly divided into treatment group (88 cases) and control group (81 cases). Observed and compared the clinical efficacy and side effects. After treatment and 3 months after treatment, the observation group “open ” period was significantly increased, while “off ” period was significantly decreased, the difference was statistically significant (P <0.05). Entecavir combined with levodopa treatment can significantly alleviate the symptoms of PD, the effect is superior to simple levodopa treatment, it is worth clinical promotion.