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在脊椎动物和非脊椎动物的神经发育过程中有大量细胞死亡。对果蝇和小鼠进行半胱氨酸天冬氨酸蛋白酶(caspase)激活的基因实验阐明了caspase通过凋亡和非凋亡机制掌控细胞命运,从而确保在神经系统发育过程中细胞合适的分化和成熟。在小鼠发育过程中,神经元死亡程序的异常影
There is a lot of cell death in the neurodevelopment of vertebrates and invertebrates. Gene experiments on cysteine aspartyl protease (caspase) activation in fruit flies and mice elucidated that caspases control cell fate through both apoptotic and non-apoptotic mechanisms to ensure proper differentiation of cells during neurodevelopment And mature. Abnormal shadow of neuronal death program during mouse development