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目的观察三角形子宫切除术对患者骨代谢及精神心理影响。方法选取因子宫良性病变行三角形子宫切除术患者50例为研究组,子宫附件正常的妇女50例为对照组。采用化学发光法及酶联免疫吸附法(ELISA法)检测术前、术后1年患者及对照组妇女血碱性磷酸酶(ALP)、骨钙素(BGP)、尿脱氧吡啶(DPD)水平。采用中国健康问卷(CHQ-12)测评术前及术后1年精神心理状况。结果三角形子宫切除组术后1年ALP、BGP、DPD水平与术前及对照组相比差异均无统计学意义(P>0.05),在精神心理方面术前、术后CHQ-12评分差异无统计学意义(P>0.05)。结论绝经前三角形子宫切除对患者骨代谢及精神心理无明显影响。
Objective To observe the effect of triangular hysterectomy on bone metabolism and mental health of patients. Methods Forty patients with benign lesions of the uterus underwent hysterectomy were selected as study group and 50 normal women with uterine attachment were selected as control group. The levels of ALP, BGP and DPD in women and controls one year before and after operation were measured by chemiluminescence and enzyme-linked immunosorbent assay (ELISA) . The Chinese mental health status (CHQ-12) was used to evaluate the mental status before and after 1 year. Results There was no significant difference in the ALP, BGP and DPD levels at 1 year after operation in the triangular hysterectomy group compared with the preoperative and control groups (P> 0.05). There was no significant difference in the psychology between preoperative and postoperative CHQ-12 scores Statistical significance (P> 0.05). Conclusions The premenopausal triangular hysterectomy had no significant effect on the bone metabolism and mental health of patients.