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目的探讨小儿肺炎支原体肺炎采用阿奇霉素序贯疗法的临床治疗效果。方法 80例肺炎支原体肺炎患儿随机分为观察组和对照组,各40例。对照组患者给予红霉素治疗(红霉素序贯疗法);观察组给予阿奇霉素治疗(阿奇霉素序贯疗法)。观察两组患儿症状改善情况,评定治疗效果。结果观察组患儿的发热、咳嗽和肺部啰音消失时间早于对照组的发热、咳嗽和肺部啰音消失时间,差异有统计学意义(P<0.05)。观察组患儿显效27例、有效11例、无效2例(显效率67.5%、有效率27.5%、无效率5.0%),总有效率为95.0%;对照组患儿显效20例、有效10例、无效10例(显效率50.0%、有效率25.0%、无效率25.0%),总有效率为75.0%。观察组总有效率高于对照组(P<0.05)。结论小儿肺炎支原体肺炎采用阿奇霉素序贯疗法的临床治疗效果显著,能够早期缓解症状,值得借鉴。
Objective To investigate the clinical effect of azithromycin sequential therapy in children with Mycoplasma pneumoniae pneumonia. Methods 80 cases of children with Mycoplasma pneumoniae pneumonia were randomly divided into observation group and control group, 40 cases in each. Patients in the control group were treated with erythromycin (sequential treatment with erythromycin) and azithromycin in the observation group (sequential treatment with azithromycin). Observe the symptom improvement of two groups of children and evaluate the treatment effect. Results The fever, cough and pulmonary rales in the observation group were earlier than those in the control group in fever, cough and pulmonary rales disappearance time, the difference was statistically significant (P <0.05). The observation group of children markedly effective in 27 cases, effective in 11 cases, 2 cases of ineffective (markedly effective rate of 67.5%, effective rate of 27.5%, efficiency of 5.0%), the total effective rate was 95.0%; control group of children markedly effective in 20 cases, effective in 10 cases , Ineffective in 10 cases (markedly effective rate of 50.0%, effective rate of 25.0%, ineffective rate of 25.0%), the total effective rate was 75.0%. The total effective rate in observation group was higher than that in control group (P <0.05). Conclusion Mycoplasma pneumoniae pneumonia with azithromycin sequential therapy of significant clinical effects, early relief of symptoms, is worth learning.