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目的:观察舒芬太尼复合酮咯酸氨丁三醇用于儿童腹部手术后的镇痛效果。方法:选择儿童腹部手术92例,随机分为观察组47例和对照组45例。对照组术后采用舒芬太尼镇痛,观察组采用舒芬太尼复合酮咯酸氨丁三醇镇痛。比较两组术后3 h、6 h、12 h、24 h和48 h的疼痛视觉模拟评分(VAS)、镇静评分(Ramsay)及术后不良反应发生情况。结果:观察组术后3 h、6 h、12 h、24 h和48 h的VSA分值均显著低于对照组(P<0.05);术后3 h、6 h、12 h、24 h Ramsay分值均显著高于对照组(P<0.05);两组术后48 h Ramsay分值比较差异不显著(P>0.05)。观察组不良反应发生率显著低于对照组(P<0.05)。结论:舒芬太尼复合酮咯酸氨丁三醇用于儿童腹部手术后镇痛效果优于单用舒芬太尼。
Objective: To observe the analgesic effect of sufentanil combined with ketorolac tromethamine for abdominal surgery in children. Methods: Ninety-two children undergoing abdominal surgery were randomly divided into observation group (n = 47) and control group (n = 45). The control group received sufentanil postoperative analgesia, and the observation group received sufentanil combined ketorolac tromethamine analgesia. The pain visual analogue scale (VAS), sedation score (Ramsay) and postoperative adverse reactions at 3 h, 6 h, 12 h, 24 h and 48 h after operation were compared between the two groups. Results: The scores of VSA at 3h, 6h, 12h, 24h and 48h after operation in observation group were significantly lower than those in control group (P <0.05). After 3 h, 6 h, 12 h, 24 h (P <0.05). The Ramsay scores at 48 h after operation were not significantly different between the two groups (P> 0.05). The incidence of adverse reactions in the observation group was significantly lower than that in the control group (P <0.05). CONCLUSIONS: Sufentanil combined with ketorolac tromethamine is superior to sufentanil alone in analgesia after abdominal surgery in children.