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[目的]观察益胃汤联合西药治疗慢性萎缩性胃炎疗效。[方法]使用随机平行对照方法,将47例门诊患者按病志号抽签法简单随机分为两组。对照组25例兰索拉唑,30mg/次,3次/d;甲硝唑,400mg/次,3次/d;左氧氟,200mg/次,3次/d。治疗组22例益胃汤(白芍、麦冬各8g,当归、丹参、沙参各12g,黄连6g,半枝莲8g,党参14g,白花蛇舌草12g,甘草、姜半夏各8g,扁豆炒12g;肠上化生加莪术8g,浙贝、水蛭各9g,白花蛇舌草25g;胃黏膜脱垂加柴胡10g,升麻、桔梗各8g,炮山甲10g;炎症、十二指肠球部溃疡加白及8g,白芷12g,海螵蛸8g;胆汁反流加郁金、竹茹、柴胡各10g;腺体不典型增生加炮山甲8g,浙贝、生牡蛎各12g;胃酸缺失加瓜蒌11g,乌梅13g),1剂/d,水煎200m L,早晚口服;西药治疗同对照组。连续治疗14d为1疗程。观测临床症状、肠化增生、腺体萎缩、不良反应。连续治疗3疗程,判定疗效。[结果]治疗组显效13例,有效8例,无效1例,总有效率95.45%。对照组显效9例,有效9例,无效7例,总有效率72.00%。治疗组疗效优于对照组(P<0.05)。症状积分治疗组改善优于对照组(P<0.05)。[结论]益胃汤联合西药治疗慢性萎缩性胃炎疗效满意,无严重不良反应,值得推广。
[Objective] To observe the therapeutic effect of Yisweitang combined with Western medicine on chronic atrophic gastritis. [Methods] Using randomized parallel control method, 47 outpatients were randomly divided into two groups randomly according to their pathological numbers. Control group, 25 cases of lansoprazole, 30mg / times, 3 times / d; metronidazole, 400mg / times, 3 times / d; levofloxacin, 200mg / times, 3 times / d. The treatment group, 22 cases of Yiwei soup (Radix Paeoniae Alba 8g, Angelica, Salvia, Radix every 12g, Coptis 6g, Scutellaria barbata 8g, Codonopsis 14g, Hedyotis diffusa 12g, licorice, ginger Pinellia each 8g, 12g; intestinal metaplasia plus Curcuma 8g, Zhejiang Pui, leeches 9g, Hedyotis diffusa 25g; gastric mucosa prolapse plus Bupleurum 10g, cohosh, Campanulaceae 8g, Cannabis 10g; inflammation, duodenum Ball ulcer plus white and 8g, Angelica 12g, sea 螵 蛸 8g; bile reflux plus turmeric, Zhuru, Bupleurum each 10g; gland atypical hyperplasia plus Cairn 8g, Zhejiang shellfish, raw oysters each 12g; Gastric acid loss plus melon 蒌 11g, plum 13g), 1 / d, decoction 200m L, morning and evening oral; Western medicine treatment with the control group. Continuous treatment 14d for a course of treatment. Observation of clinical symptoms, intestinal hyperplasia, glandular atrophy, adverse reactions. Continuous treatment of 3 courses to determine the efficacy. [Results] The treatment group was markedly effective in 13 cases, effective in 8 cases, ineffective in 1 case, the total effective rate was 95.45%. In the control group, 9 cases were markedly effective, 9 cases were effective, 7 cases were ineffective, and the total effective rate was 72.00%. The treatment group was better than the control group (P <0.05). The symptom score improved better than the control group (P <0.05). [Conclusion] Yiwei Decoction combined with Western medicine in the treatment of chronic atrophic gastritis has satisfactory curative effect and no serious adverse reactions, which deserves promotion.