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目的 探讨血清谷丙转氨酶 (ALT)水平与肝脏病理改变的关系。方法 对 6 5 1例病理确诊的各型肝炎患者 ,按肝穿时ALT水平高低 ,用SPSS 8 0软件分析。结果 各型肝炎血清ALT水平依次为急性肝炎 (AH) >慢性肝炎 (CH)中 >CH重 >CH轻 >活动性肝硬变 (ALC) >静止性肝硬变 (SLC) ;ALT正常组 86例中 ,10 5 %肝组织正常 ;仅中度ALT异常的CH组血清ALT与肝病理损害程度弱相关 (r =0 189,P =0 0 0 6 )。结论 血清ALT水平与肝脏病理改变程度无明确相关性。
Objective To investigate the relationship between the serum level of alanine aminotransferase (ALT) and hepatic pathological changes. Methods Totally 651 patients with pathologically diagnosed hepatitis were divided into two groups according to the level of ALT during liver perfusion and analyzed by SPSS 80 software. Results Serum levels of ALT in each type of hepatitis were as follows: acute hepatitis (AH)> chronic hepatitis (CH)> CH weight> CH light> active cirrhosis (ALC)> static cirrhosis (SLC) In our study, 10 5% of the liver tissues were normal. Serum ALT in CH patients with moderate ALT only was weakly associated with the degree of liver damage (r = 0 189, P = 0 0 6). Conclusion There is no clear correlation between the level of serum ALT and the degree of liver pathological changes.