1病例资料患者男,65岁,主诉:反复咳嗽、咳痰12年,活动后气促6年,再发加重1月,入院治疗。缘于12年前受凉后出现咳嗽,呈阵发性咳嗽,每次2~4声,以晨起时为甚,同时咳较多的黄色黏痰,量约15 m L/d,偶带少许白色泡沫痰,无痰中带血,无畏寒、发热、盗汗、胸痛、胸闷、气促,无流涕、鼻塞,自行给予“头孢、左氧氟沙星”等药物口服后症状可好转。后上述症状反复发作,以受凉感冒或冬春季多见,全年累计 1 case data patient male, 65 years old, chief complaint: repeated cough, sputum for 12 years, six months after the event of shortness of breath, recurrence increased in January, admitted to hospital. Due to 12 years ago after the onset of cold cough, paroxysmal cough, 2 to 4 times each sound, even in the morning, cough and more yellow phlegm, the amount of about 15 m L / d, even with a little White foam sputum, no sputum blood, no chills, fever, night sweats, chest pain, chest tightness, shortness of breath, no runny nose, nasal congestion, given their own “cephalosporins, levofloxacin ” and other drugs after oral administration can be improved. After the recurrence of the above symptoms, to catch a cold or more common in winter and spring, accumulated throughout the year