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对３２例脑梗塞患者及１８例脑出血患者外周血单个核细胞（ＰＢＭＣ）ＩＬ－６和ＴＮＦα分泌水平进行了测定。结果表明：脑梗塞及脑出血患者ＩＬ－６水平分别为６３６．１３±７３．６２ｕ／ｍｌ和５６１．１１±８６．７２ｕ／ｍｌ；ＴＮＦα水平分别为１０５．２２±１８．１４ｕ／ｍｌ和７１．９４±１０．６４ｕ／ｍｌ。２４例健康老年人及２０例健康献血员ＩＬ－６水平分别为２６９．４６±３７．４９ｕ／ｍｌ和１６．７６±３．１６ｕ／ｍｌ；ＴＮＦα水平分别为２２．２０±４．６２ｕ／ｍｌ和９．１２±２．１４ｕ／ｍｌ。各组之间Ｐ值均小于０．０１，有显著差异。提示ＩＬ－６及ＴＮＦα与脑梗塞及脑出血的发病有一定相关性；老年人ＩＬ－６及ＴＮＦα水平有所改变。
The levels of IL-6 and TNFα in peripheral blood mononuclear cells (PBMCs) of 32 patients with cerebral infarction and 18 patients with cerebral hemorrhage were measured. The results showed that the levels of IL-6 in cerebral infarction and intracerebral hemorrhage were 636.13 ± 73.62u / ml and 561.11 ± 86.72u / ml respectively; the levels of TNFα were 105.22 ± 18.14u / ml and 71 .94 ± 10.64 u / ml. The levels of IL-6 in 24 healthy elderly and 20 healthy blood donors were 269.46 ± 37.49u / ml and 16.76 ± 3.16u / ml respectively; the levels of TNFα were 22.20 ± 4.62u / ml And 9.12 ± 2.14 u / ml. P values of all groups were less than 0.01, there was a significant difference. These results suggest that IL-6 and TNFα may be related to the incidence of cerebral infarction and cerebral hemorrhage. The levels of IL-6 and TNFα in the elderly are changed.