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本文测定了64例糖尿病患者24小时尿N-乙酰-β-D-氨基葡萄糖苷酶(NAG)活性及其同功酶NAG-B含量。结果表明:在糖尿病早期即有尿NAG活性增高。在糖尿病伴肾损害者,尿NAG、NAG-B活性均明显上升。同时还讨论了血清NAG活性与微血管病变的关系。
In this study, 24-hour urine N-acetyl-β-D-glucosaminidase (NAG) activity and its isoenzyme NAG-B content were measured in 64 patients with diabetes mellitus. The results showed that in the early stage of diabetes that is increased urine NAG activity. In diabetic patients with renal damage, urinary NAG, NAG-B activity were significantly increased. Also discussed the relationship between serum NAG activity and microvascular disease.