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甘油三酯脂肪酶(ATGL)家族是孕期母体脂质代谢的关键酶,通过水解脂蛋白的甘油三酯和磷脂以释放游离脂肪酸,使母体的脂质转运给胎儿。多项研究表明,子痫前期(PE)孕妇体内多存在脂质代谢紊乱,并与ATGL基因表达异常密切相关。
The triglyceride lipase (ATGL) family is a key enzyme in maternal lipid metabolism during pregnancy and releases maternal lipids to the fetus by hydrolyzing lipoprotein triglycerides and phospholipids to release free fatty acids. A number of studies have shown that pregnant women with preeclampsia (PE) there are more lipid metabolism disorder, and ATGL gene expression is closely related.