早在二十世纪初,人们就开始应用蛇毒来缓解恶性肿瘤疼痛、神经痛和关节痛。1933年Calmette及Taguet先后发现肌肉注射微量眼镜蛇毒具有类似吗啡样的中枢性镇痛作用。此后Macht和Steinbrocker等不少学者也相继报告了类似的结果。之后.其它含有神经毒素的蛇毒也先后被发 As early as the beginning of the 20th century, people began to use snake venom to relieve malignant tumor pain, neuralgia and joint pain. In 1933, Calmette and Taguet successively found that the intramuscular injection of micro cobra venom has a similar morphine-like central analgesic effect. Since then, many scholars such as Macht and Steinbrocker have also reported similar results. After that, other snake venoms containing neurotoxins were also issued