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对84例消化性溃疡患者血清LPO含量及Gu，Zn—SOD活性进行了测定。发现胃溃疡及复合性溃疡患者血清LPO含量明显高于正常对照（P＜0．001），血清Cu，Zn—SOD活性明显低于正常对照（P＜0．01）；十二指肠球部溃疡患者血清LPO含量有升高趋势，而血清Gu，Zn－SOD活性在正常范围。结果提示：胃溃疡的发生可能与氧自由基的作用有关。
84 cases of peptic ulcer patients serum LPO content and Gu, Zn-SOD activity were measured. The levels of serum LPO in patients with gastric ulcer and compound ulcer were significantly higher than those in normal control (P <0.001), and the activities of Cu and Zn-SOD in serum were significantly lower than those in normal control (P <0.01) Serum LPO levels in ulcer patients tended to increase, while serum Gu and Zn-SOD activities were in the normal range. The results suggest that: the occurrence of gastric ulcer may be related to the role of oxygen free radicals.