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目的:探讨妊娠晚期血红蛋白(Hb)水平对妊娠不良结局的影响。方法:选择妊娠晚期住院分娩的产妇627例,根据Hb水平分为4组,即高水平组(A组)237例:Hb≥135g/L;正常高限组(B组)122例:Hb 127~134g/L;正常组(C组)130例:Hb 119~126g/L;正常低限组(D组)138例:Hb≤118g/L。采用自动血球计数仪检测Hb。比较各组糖代谢异常、妊娠期高血压疾病、早产等并发症,以及新生儿低出生体重发生情况。结果:A组糖代谢异常和早产发生率,均显著或非常显著高于其他3组(P<0.05,P<0.01);妊娠期高血压疾病发生率显著高于D组(P<0.05),低出生体重发生率非常显著高于C组(P<0.01)。B组糖代谢异常发生率非常显著高于D组(P<0.01),低出生体重发生率显著高于C组(P<0.05)。结论:妊娠晚期高Hb水平,会增加糖代谢异常、妊娠期高血压疾病、早产和低出生体重等的发生风险。
Objective: To investigate the influence of hemoglobin (Hb) in late pregnancy on adverse pregnancy outcome. Methods: A total of 627 pregnant women in hospital delivery during the third trimester of pregnancy were enrolled. According to the Hb level, they were divided into 4 groups: 237 in the high-level group (group A): Hb≥135g / L; 122 in the high- ~ 134g / L; 130 normal subjects (group C): 119 ~ 126g / L Hb; 138 normal subjects (group D): Hb≤118g / L. Hb was detected by automatic hemacytometer. Compare the abnormal glucose metabolism, hypertensive disorder complicating pregnancy, premature labor and other complications, and neonatal low birth weight. Results: The incidence of abnormal glucose metabolism and preterm birth in group A were significantly or very significantly higher than those in the other three groups (P <0.05, P <0.01). The incidence of hypertensive disorder in pregnancy was significantly higher than that in group D (P <0.05) The incidence of low birth weight was significantly higher than the C group (P <0.01). The incidence of abnormal glucose metabolism in group B was significantly higher than that in group D (P <0.01), and the incidence of low birth weight was significantly higher than that in group C (P <0.05). Conclusion: The high Hb level in late pregnancy may increase the risk of abnormal glucose metabolism, hypertensive disorder complicating pregnancy, premature birth and low birth weight.