论文部分内容阅读
目的探讨成人型肺母细胞瘤的临床病理学特点及鉴别诊断。方法收集9例成人型肺母细胞瘤，复习患者病历档案并进行组织学观察和随访。结果9例成人型肺母患者年龄为31～78岁，平均52岁。获访的8例患者7例病故于术后5～18个月，术后平均生存10．3个月。肿瘤位于肺门（中央型）者2例，位于周边肺膜下（周围型）者7例；组织学表现为双相型者8例：既有复杂的胚胎性腺管结构又有幼稚的始基成分和分化程度不等的梭形细胞。上皮型者1例：主要由复杂的分枝状腺管构成。部分腺上皮形态相似于子宫内膜样腺体。结论成人型肺母是一恶性度极高的肿瘤，高发年龄为50岁左右。诊断上应注意与肺的癌肉瘤、肺腺癌及儿童型肺母等鉴别。
Objective To investigate the clinicopathological characteristics and differential diagnosis of adult human pulmonary blastoma. Methods Nine cases of adult human pulmonary blastoma were collected and their medical records were reviewed and histological observation and follow-up were performed. Results The ages of nine adult pulmonary patients ranged from 31 to 78 years and averaged 52 years. Among the 8 patients admitted to the hospital, 7 patients died within 5 to 18 months after surgery, and the average survival time was 10.3 months. The tumors were located in the hilar (central type) in 2 patients and in the subperipheral subpericardium (peripheral type) in 7 patients; histological manifestations were biphasic in 8 patients: both complex embryonic gonad structures and naive primordia Spindle cells with varying composition and differentiation. Epithelial type 1 case: mainly composed of complex branched ducts. Some glandular epithelial morphology is similar to endometrioid glands. Conclusions Adult pneumoconiosis is a very malignant tumor with a high age of about 50 years. Diagnosis should be noted with the lung cancer sarcoma, lung adenocarcinoma and children’s lung mother and other identification.