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目的通过对梅毒血清学试验TRUST、TPPA检测结果分析,了解本地梅毒感染情况并比较两种检测方法的特点。方法统计分析2007年8月1日～2008年7月31日1年内在皮肤科实验室进行的10584人次TRUST检测和4083人次TPPA检测结果。结果10583人次TRUST检测中阳性428人次,阳性率为4.04%。4078人次TPPA检测中阳性425人次,阳性率为10.42%。TPPA的阳性率明显高于TRUST,两者的差异具有统计学意义。TRUST试验中女性的阳性率明显低于男性,TPPA试验中女性的阳性率高于男性,差异具有统计学意义。TRUST阳性主要为低滴度阳性。18～29、30～39岁两个年龄组检出的阳性例数最多且阳性率较高。结论女性感染者多于男性感染者,梅毒血清阳性者主要集中在18～39岁年龄组,是梅毒防治的重点。
Objective To analyze the results of TRUST and TPPA tests on syphilis serology to understand the local syphilis infection and to compare the characteristics of the two detection methods. Methods The data of 10 844 TRUST tests and 4083 TPPA tests conducted in dermatology laboratories from August 1, 2007 to July 31, 2008 were statistically analyzed. RESULTS: There were 4283 positive TRUST tests in 10 053 patients, the positive rate was 4.04%. 4078 people TPPA test positive 425 people, the positive rate was 10.42%. The positive rate of TPPA was significantly higher than TRUST, the difference between the two was statistically significant. The TRUST test positive rate of women was significantly lower than men, TPPA test, the positive rate of women than men, the difference was statistically significant. TRUST positive mainly low-titers. 18 ~ 29,30 ~ 39 years old two groups detected the highest number of positive cases and a higher positive rate. Conclusion There are more women infected with HIV than those infected with HIV, and syphilis seropositive mainly concentrated in the age group of 18-39 years, which is the focus of syphilis prevention and treatment.