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胰腺炎早期胰蛋白酶进入胰实质,是引起胰腺炎一系列病理生化反应和临床表现的关键,因此胰蛋白酶-激肽释放酶抑制剂——Trasylol(抑肽酶)对胰腺炎有良好疗效,但部分患者在反复应用该药后可因免疫作用导致过敏性休克。1968年作者等发现叶绿素A(Chlorophyll-A)的某些衍化物有抑制胰蛋白酶活性的作用,并应用于治疗慢性胰腺炎。本文报道1968～1973年间采用叶绿素A水溶剂治疗34例慢性复发性胰腺炎的临床疗效,并加以讨论。 34例中男性20例,女性14例。年龄除1例80岁外余为27～64岁。15例住院治疗,19例门诊治疗。根
Early pancreatic trypsin into the pancreatic parenchyma, pancreatic inflammation is caused by a series of pathological and biochemical reactions and clinical manifestations of the key, so trypsin - kallikrein inhibitor - Trasylol (aprotinin) on pancreatitis has a good effect, but Some patients after repeated application of the drug may lead to anaphylactic shock due to immune function. In 1968, the authors found that some derivatives of Chlorophyll-A had the effect of inhibiting trypsin activity and were applied to the treatment of chronic pancreatitis. This article reports the clinical efficacy of chlorophyll-A aqueous solution in the treatment of 34 patients with chronic recurrent pancreatitis between 1968 and 1973, and discussed. 34 cases of 20 males and 14 females. Except for 1 case of 80-year-old outside of 27 to 64 years old. 15 hospitalized, 19 outpatient treatment. root