【摘 要】
：
采用溶胶凝胶自蔓延法制备了不同配比的SiO2-CaO-P2O5-MgO系生物活性玻璃粉,并通过压制烧结工艺制成块状玻璃陶瓷材料.研究了材料的组织结构、力学性能和在骨内种植试验中的
【机 构】
：
西北有色金属研究院,西安交通大学,第四军医大学
论文部分内容阅读
采用溶胶凝胶自蔓延法制备了不同配比的SiO2-CaO-P2O5-MgO系生物活性玻璃粉,并通过压制烧结工艺制成块状玻璃陶瓷材料.研究了材料的组织结构、力学性能和在骨内种植试验中的生物学行为.结果表明:经过1100℃烧结热处理后,凝胶玻璃基体中析出(Ca,Mg)3(PO4)2晶体和MgSiO3晶体,其中,硅含量较高的样品中析出晶体的尺寸较大,具有较高的弯曲强度和断裂韧性值,分别可达172 MPa和2.02 MPa.m1/2.两种材料植入动物体内后与骨组织接触良好,未见明显的炎症反应.其中硅含量较高的样品植入骨内仅3周即可在骨与材料接触面处生成大量新生血管和骨小梁,植入6周后即与骨融合,两者之间钙磷含量较高且连续,没有明显的界面,这些结果证明该材料具有良好的骨组织相容性,是一种较为理想的骨修复替代材料.
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