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目的:探讨医院药品不良反应(ADR)的发生情况及引发ADR的相关因素。方法:将医院2007年收集到的120例ADR进行分类汇总分析。结果:120例ADR中,化学药品引发102例,中成药引发18例。在102例化学药品所致ADR中,静脉给药引发者最多,占总例数的88.33%;抗微生物药引起的ADR居首位;皮肤及附件损害是ADR的最主要表现,占总例数的41.67%,而较严重的ADR有11例。结论:ADR的发生与给药途径、药品种类等多种因素相关,应加强对ADR的监测及相关知识的宣传,以减少和避免ADR的发生。
Objective: To investigate the incidence of adverse drug reaction (ADR) in hospital and the related factors of ADR. Methods: A total of 120 ADRs collected by the hospital in 2007 were collected and analyzed. Results: Of the 120 cases of ADR, 102 cases were caused by chemical drugs and 18 cases were caused by proprietary Chinese medicines. Among the 102 ADRs caused by chemical drugs, intravenous administration was the most frequently initiated, accounting for 88.33% of the total cases; ADR caused by antimicrobials ranked first; skin and accessory damage were the most important manifestations of ADR, accounting for the total number of cases Of 41.67%, while the more severe ADR in 11 cases. Conclusion: The occurrence of ADR is related to many factors such as the route of administration, the type of drug and so on. Monitoring of ADR and publicity of related knowledge should be strengthened to reduce and avoid the occurrence of ADR.