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目的探讨血清甲胎蛋白(AFP)、a-L-岩藻糖苷酶(AFU)和γ-谷氨酰转移酶(GGT)联合检测对原发性肝癌(primary hepatocarcinoma,PHC)的诊断价值。方法对85例原发性肝癌患者血清中AFP、AFU和GGT进行联合检测并分析。结果原发性肝癌患者血清AFP、AFU和GGT水平较正常对照组有统计学差异(P<0.01);联合检测的敏感性和诊断准确性均比单项检测高。结论联合检测血清中的AFP、AFU和GGT可提高对原发性肝癌的检出率,具有较大的临床意义。
Objective To investigate the diagnostic value of serum alpha-fetoprotein (AFP), a-L-fucosidase (AFU) and gamma-glutamyl transferase (GGT) in the diagnosis of primary hepatocarcinoma (PHC) Methods Serum AFP, AFU and GGT in 85 patients with primary liver cancer were detected and analyzed. Results Serum levels of AFP, AFU and GGT in patients with primary liver cancer were significantly higher than those in controls (P <0.01). The sensitivity and diagnostic accuracy of combined detection were higher than those of single test. Conclusion Combined detection of serum AFP, AFU and GGT can improve the detection rate of primary liver cancer, which has great clinical significance.