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食管肉瘤样癌是一种十分罕见的食管恶性肿瘤,无特异性临床症状及体征,主要表现为吞咽梗阻、胸骨后疼痛等;其生长速度较快,常呈息肉样生长;具有上皮性癌和梭性肉瘤样细胞2种成分,并以肉瘤样成分占优势,其发病原因及病理组织起源目前尚未明确;免疫组织化学检测癌成分常见细胞角蛋白及上皮膜抗原表达,肉瘤样成分常见波形纤维蛋白表达;治疗方式以手术为主,对放射治疗、化学疗法(化疗)较敏感,常用化疗方案为铂类联合氟尿嘧啶类或紫杉类的双药联合方案,其早期预后较食管鳞状细胞癌好。
Esophageal sarcomatoid carcinoma is a very rare esophageal malignant tumor with no specific clinical symptoms and signs, mainly manifested as swallowing obstruction, post-sternal pain; its growth rate is relatively fast, often polypoid growth; with epithelial carcinoma and There are two components of shuttle-type sarcomatoid cells, which are dominated by sarcomatoid components. The etiopathogenisis and the origin of pathological tissue are not yet clear. Immunohistochemistry is used to detect the expression of common cytokeratin and epithelial membrane antigen in cancer cells. Protein expression; treatment is mainly surgery, radiation therapy, chemotherapy (chemotherapy) are more sensitive, commonly used chemotherapy for platinum combined fluorouracil or taxane dual drug combination program, the early prognosis of esophageal squamous cell carcinoma it is good.