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目的 探讨腹腔镜下卵巢表面电凝术对多囊卵巢综合征 (PCOS)所致不孕症患者的疗效。方法 对31例PCOS不孕症患者观察术前术后血黄体生成素 (LH)、卵泡刺激素 (FSH)、睾酮 (T)水平 ,术后排卵情况、妊娠率及妊娠结果。结果 31例患者中失访 3例 ,除 1例术后 3个月应用克罗米芬 (CC)一个疗程后恢复月经外 ,月经情况均明显改善。术后LH、LH/FSH和T均较术前明显降低 ,而FSH明显升高 ,差异具有显著性 (P <0 0 1)。术后排卵率为 89 3% (2 5 / 2 8) ,排除干扰因素后妊娠率为 70 6 % (12 / 17) ,早期流产率为 15 4% (2 / 13) ,术后附件区粘连的发生率为 14 3% (3/ 2 1)。结论 腹腔镜下卵巢表面电凝术治疗PCOS相对于促性腺激素治疗和卵巢楔切术具有术后排卵率高、妊娠率高、流产率低、并发症少的优点 ,是CC治疗失败后的一个有效治疗手段。
Objective To investigate the effect of laparoscopic ovarian surface electrocoagulation on infertility caused by polycystic ovary syndrome (PCOS). Methods 31 cases of PCOS infertility patients were observed before and after the blood serum LH, FSH and T levels, postoperative ovulation, pregnancy rate and pregnancy outcome. Results Of the 31 patients, 3 were lost to follow-up. The menstrual conditions were significantly improved except for 1 patient who recovered after a course of treatment with clomiphene citrate (CC) 3 months after operation. The postoperative LH, LH / FSH and T were significantly lower than those before the operation, while FSH was significantly increased, the difference was significant (P <0.01). The ovulation rate was 89.3% (2 5/28) after operation, the pregnancy rate was 70.6% (12/17) after removing the interference factors, and the rate of early abortion was 15.4% (2/13) The incidence was 14 3% (3/2 1). Conclusions Laparoscopic treatment of ovarian surface electrocoagulation with PCOS relative to gonadotropin treatment and ovarian wedge resection has the advantages of high rate of postoperative ovulation, high pregnancy rate, low abortion rate and fewer complications, which is one of the post-CC treatment failures Effective treatment.