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目的:总结妊娠期用药原则,加强管理,做到合理用药,保证孕妇和胎儿双重安全。方法:选取2013年6月~2014年6月,枣庄市中医医院孕妇门诊接诊的由不合理用药对孕妇或胎儿造成伤害的病例,共计132例,对其临床资料进行统计、分析。总结药物对孕妇或胎儿造成的影响及孕妇的用药原则。结果:调查发现,妊娠期不安全不合理使用药物包括选药不当48例、重复性用药28例、不良反应23例、用法用量不当16例,以及其他不安全因素17例。其中选药不当占的比重较大,占36.4%。妊娠期不合理用药造成的后果包括早产48例,胎儿唇裂15例,胎儿肢体短缺7例,胎儿智力低下15例,胎儿心动过缓33例和其他症状14例。结论:对于妊娠期用药要加强管理,选择安全有效药物,做到合理用药,并兼顾孕妇和胎儿双重安全,减少伤害。
OBJECTIVE: To summarize the principles of medication during pregnancy, strengthen management, make rational use of drugs and ensure the double safety of pregnant women and fetus. Methods: From June 2013 to June 2014, a total of 132 cases of maternal or fetal injury caused by irrational use of medication in pregnant women’s outpatient clinic of Zaozhuang Chinese Medicine Hospital were selected. Their clinical data were statistically analyzed. Summarize the impact of drugs on pregnant women or fetuses and pregnant women medication principles. Results: The survey found that unsafe and unreasonable use of drugs in pregnancy, including improper drug selection 48 cases, 28 cases of repeated medication, adverse reactions in 23 cases, 16 cases of inappropriate usage, and other 17 cases of unsafe factors. Which accounted for a larger proportion of inappropriate drug accounting, accounting for 36.4%. The consequences of irrational use of medication during pregnancy include 48 cases of preterm delivery, 15 cases of fetal cleft lip, 7 cases of fetal limb shortness, 15 cases of fetal mental retardation, 33 cases of fetal bradycardia and 14 cases of other symptoms. Conclusion: For the medication during pregnancy to strengthen management, select safe and effective drugs, so that rational use of drugs, and take into account the dual safety of pregnant women and fetuses to reduce injuries.