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随着干细胞生物学和肿瘤学的深入研究,Reya[1]从干细胞和肿瘤细胞部分相似的生物学特性出发提出了“肿瘤干细胞假说,”认为肿瘤组织中存在极少量的具有无限增殖和分化潜能的肿瘤干细胞,正是这群特异性细胞促使肿瘤的产生和发展。该假说对肿瘤的细胞起源,发生模式和临床诊疗等方
With a thorough study of stem cell biology and oncology, Reya [1] put forward the “tumor stem cell hypothesis” from the similar biological characteristics of stem cells and tumor cells, that there is a very small number of cells with unlimited proliferation and differentiation potential in tumor tissues Of tumor stem cells, it is this group of specific cells to promote tumor formation and development. The hypothesis on tumor cell origin, patterns of occurrence and clinical diagnosis and treatment