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目的 分析神经阻滞剂引起急性肌张力障碍的相关因素。方法 查阅山东省济宁市精神病防治院精神科1997年全部出院病历,选取其中应用神经阻滞剂者,对发生急性肌张力障碍和未发生者诸多因素进行比较。结果 急性肌张力障碍发生率为22.8％,年龄小,男性,病情严重,既住有锥体外系副反应史,应用高效价药物,剂量大者发生率高;用药早期危险性大,合并抗胆碱能药物者发生率低。结论 精神科临床医生选择治疗方案时适当参考以上指标,对预防急性肌张力障碍的发生定有裨益。
Objective To analyze the related factors of acute dystonia induced by nerve blockers. Methods Jining City, Shandong Province, psychiatric prevention and treatment of psychiatric hospital all discharged from hospital records in 1997, selected among those who use nerve blockers, occurred in acute dystonia and a number of factors were compared. Results The incidence of acute dystonia was 22.8%. The incidence of acute dystonia was very young. The prevalence of acute dystonia was high in both men and women. The incidence of extrapyramidal side effects was high. Alkalipathic drugs are low incidence. Conclusion Psychiatrist clinicians choose the appropriate treatment options refer to the above indicators, the prevention of acute dystonia will be helpful.