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报道15例施行同种异体肾移植病人,原发病为慢性肾小球肾炎12例,药物性肾病、盆腔异位肾损伤及多囊肾各1例。术后免疫抑制药物采用环孢素A、硫唑嘌呤及强的松三联用药,出现急性排异时应用甲基强的松龙冲击疗法,移植肾功能可逆转。结果术后存活2~28个月14例,肾功能良好;1例术后26个月死于心肌梗塞。认为同种异体肾移植是治疗终末期肾病的有效方法。
Reported 15 cases of allogeneic kidney transplantation patients, the primary disease was chronic glomerulonephritis in 12 cases, drug-induced nephropathy, pelvic ectopic kidney injury and polycystic kidney disease in 1 case. Postoperative immunosuppressive drugs using cyclosporine A, azathioprine and prednisone triple therapy, acute rejection when the application of methylprednisolone impact therapy, renal transplant function can be reversed. Results Postoperative survival of 14 cases of 2 to 28 months, renal function was good; 1 patient died of myocardial infarction 26 months after operation. Allograft renal transplantation is considered an effective method of treatment of end-stage renal disease.