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用HRP逆行追踪术观察了大鼠下丘脑交叉上核的传出投射,并进一步通过HRP逆行追踪结合免疫组化的方法观察了交叉上核投射神经元的性质.结果表明:交叉上核有稀疏的投射分布到下丘脑前核前部、腹内侧核、背内侧核、室周核、背侧区、丘脑室旁核和带旁核.交叉上核投射的主要靶区是下丘脑室旁核下区和室旁核,交叉上核的加压素能和血管活性肠肽能神经元参与这一投射.另外,HRP逆行追踪表明除本实验所涉及的神经肽外,还有其他神经递质参与这一投射.文内还就交叉上核向下丘脑室旁核下区和室旁核的投射及其化学性质进行了讨论.
The HRP retrograde tracing technique was used to observe the projecting projection of the suprachiasmatic nucleus of the rat and the HRP retrograde tracing combined with immunohistochemistry was used to observe the properties of neurons projecting from the suprachiasmatic nucleus.The results showed that there were sparse Of the projections to the anterior hypothalamic nucleus, ventral medial nucleus, dorsal medial nucleus, periventricular nucleus, dorsal metacarpophalamic paraventricular nucleus and paraventricular nucleus.The main target of the suprachiasmatic nucleus projection is hypothalamic paraventricular nucleus The hypothalamic and paraventricular nuclei, the vasopressin on the suprachiasmatic nucleus, and the vasoactive intestinal peptide neurons are involved in this projection. In addition, HRP retrograde tracing showed that in addition to the neuropeptides involved in this experiment, there are other neurotransmitters involved This projection also discusses the projection of the suprachiasmatic nucleus into the paraventricular nucleus and paraventricular nucleus of the hypothalamus and its chemical properties.