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目的观察苯巴比妥钠预防早产儿颅内出血的疗效,探讨其对本病的临床应用价值。方法回顾分析出生后应用苯巴比妥钠静脉注射的早产儿病例,共39例,其中,男25例,女14例;所有患儿出生后均于24小时内静脉注射苯巴比妥,连续3天。纠正胎龄12月时行头颅CT检查,观察其预防颅内出血的疗效。结果在纠正胎龄12月时,CT示颅内出血7例,颅内出血发生率为17.9%,较文献报道为低。结论出生后早期应用苯巴比妥钠能对早产儿颅内出血起一定的预防作用。
Objective To observe the curative effect of phenobarbital sodium in preventing intracranial hemorrhage in premature infants and discuss its clinical value of this disease. Methods A retrospective analysis of phenobarbital sodium after birth by intravenous injection of 39 cases of premature children, including 25 males and 14 females; all children were born within 24 hours after intravenous injection of phenobarbital, continuous 3 days. Correct gestational age in December when head CT examination to observe the effect of preventing intracranial hemorrhage. Results Correction of gestational age in December, CT showed intracranial hemorrhage in 7 cases, the incidence of intracranial hemorrhage was 17.9%, lower than reported in the literature. Conclusion Early postnatal application of phenobarbital sodium can play a preventive role in premature children intracranial hemorrhage.